New triterpene diglycosides from the rhizome of Cimifuga foetida.

Five new 9,19-cycloartane triterpene diglycosides, which have been named cimiaceroside C (1), and cimifosides A-D (2-5) together with the known compounds cimiracemoside D (6), cimidahurine (7) and alpha-D-glucopyranosyl-l-beta-D-fructofuranoside (8) were isolated from the rhizome of Cimicifuga foetida. The new triterpene diglycosides 1-5 were identified as cimiacerol-3-O-beta-D-xylopyranosyl-(1''-->3')-beta-D-xylopyranoside, 12beta-hydroxycimigenol-3-O-beta-D-xylopyranosyl-(1''-->3')-beta-D-xylopyranoside, 25-Oacetylcimig-enol-3-O-beta-D-xylopyranosyl-(1''-->3')-beta-D-xylopyranoside, 24- acetylhydroshengmanol-3-O-beta-D-xylopyranosyl-(1''-->3')-beta-D-xylopyranoside and 26-deoxyacetylacteol-3-O-beta-D-xylo- pyranosyl-(1''-->3')-beta-D-xylopyranoside, respectively, based on analysis of their spectral data and chemical reactions.